I have been prescribed Comtess and Rasagiline as an addition to Madopark and Requip Depot. This has had several positive effects, but also one negative one. The problem is that I get diarrhoea and I have to go to the toilet constantly, morning and evening. Is this harmful? Even though it’s a nuisance, I think constipation is worse. Should I take any over-the-counter medicine for diarrhoea? I’d be grateful for any advice.

Comtess can cause diarrhoea in at least 10 per cent of users. This isn’t sustainable in the long run, so it might be a good idea to stop taking it and instead increase your levodopa dose slightly. If you’re experiencing temporary diarrhoea, you can take over-the-counter medication, but it’s not advisable to take it continuously. /Dag Nyholm