When should I start reducing my working hours? I’m at an early stage with fairly mild symptoms, but I’m so terribly tired that I find it hard to muster the energy to exercise and keep active as I should. I enjoy my job and it’s a shame to think that my career is over (well, at any rate, I don’t think I’ll have the energy to progress any further). Do you have any advice you could offer?

There’s no specific point in time when you should reduce your working hours, but the tiredness you describe could be a reason to try, for example, working 75 per cent of full-time hours instead of 100 per cent. You may need a slightly longer recovery period than is possible whilst working full-time. It’s worth noting that fatigue could be a side effect of dopamine agonists or low blood pressure, or alternatively another condition such as anaemia, etc. But of course, it may also be part of the illness itself. /Dag Nyholm